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Search Result

Search Results for " alk 1 "

Targets

FAK IGF-1R ALK

39

Compounds

1760

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T10285 ALK inhibitor 1 FAK , IGF-1R , ALK
ALK inhibitor 1 is a selective ALK kinase inhibitor.
T11184 EML4-ALK kinase inhibitor 1 EML4 ALK kinase inhibitor 1,EML4-​ALK kinase inhibitor 1 ALK
EML4-ALK kinase inhibitor 1 (EML4 ALK kinase inhibitor 1) is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM.
T6409 ALK kinase inhibitor-1 SAR348830 Others
SAR348830 is an ALK inhibitor, targeting anaplastic lymphoma kinase.
T3059 ALK-IN-1 AP26113,Brigatinib,AP26113-analog EGFR , IGF-1R , ALK
ALK-IN-1 (AP26113) is a potent ALK inhibitor with IC50 of 0.62 nM in a cell-free assay, demonstrated ability overcome Crizotinib resistance mediated by a L1196M mutation. Phase 2.
T10286 ALK/ROS1-IN-1 Others
ALK/ROS1-IN-1 is a potent and selective anti-crizotinib-resistant ALK/ROS1 dual inhibitor (IC50s: 0.530 μM and 0.174 μM for ROS1 and ALK enzyme).
T11254 F-1 ROS , ALK , ROS Kinase
F-1 is IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively. F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathwa...
T4015 HG-14-10-04 ALK
HG-14-10-04 is a potent and specific ALK inhibitor.
T2641 KRCA-0008 KRCA 0008,KRCA0008 ACK , ALK
KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays drug-like properties without hERG liability.
T16708 R-268712 ALK , TGF-beta/Smad
R-268712 is a specific activin receptor-like kinase 5 (ALK5) inhibitor(IC50 of 2.5 nM). It is also an orally active transforming growth factor-β type I receptor inhibitor.
T79392 ALK/EGFR-IN-1 EGFR
ALK/EGFR-IN-1 (Compound 8l) is a dual inhibitor targeting both ALK and EGFR, effectively blocking their phosphorylation. It demonstrates potent inhibition of ALK/EGFR mutants with IC50 values of 4.3 nM for EGFR L858R T79...
T2251 NVP-TAE 684 TAE684 Apoptosis , ALK
NVP-TAE 684 (TAE684) is a excellently effective and specific ALK inhibitor(IC50=3 nM).
T72931 TRK/ALK-IN-1
TRK/ALK-IN-1 is a potent dual inhibitor of TRK and ALK, exhibiting good correlation between its enzymatic inhibition and anti-proliferative activities, with IC50 values of 2.2 nM for TRKA, 9.3 nM for ALK WT, and 38 nM fo...
T67699L ALK/ROS1 inhibitor 2e HCL (R)-1-(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide hydrochloride(2365497-12-5 Free base) Apoptosis
ALK/ROS1 inhibitor 2e HCL possesses anti-apoptotic, anti-proliferative and anti-tumour activities.
T1936 Alectinib RG-7853,AF802,CH5424802,AF-802 VEGFR , Tyrosine Kinases , ALK
Alectinib (RG-7853) is an orally available inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with antineoplastic activity.
T3678 Entrectinib RXDX-101,NMS-E628 Trk receptor , ROS , ALK , Autophagy , ROS Kinase
Entrectinib (RXDX-101) is an inhibitor of TrkA (IC50: 1.7 nM), TrkB (IC50: 0.1 nM), and TrkC (IC50: 0.1 nM), as well as anaplastic lymphoma kinase (ALK; IC50: 1.6 nM) and C-ros oncogene 1 (ROS1; IC50: 0.2 nM). Entrectini...
T8387 Alectinib hydrochloride CH5424802 (Hydrochloride),AF-802 (Hydrochloride),RO5424802 (Hydrochloride) ALK
Alectinib hydrochloride (RO5424802 Hydrochloride) is a selective, and orally available inhibitor of ALK( IC50 : 1.9 nM)
T3061 Lorlatinib PF-6463922,PF-06463922,Loratinib Apoptosis , Tyrosine Kinases , ROS , ALK , ROS Kinase
Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (Ros1), with potential antineoplastic activity.
T76858 Ascrinvacumab PF-03446962 ALK , TGF-beta/Smad
Ascrinvacumab (PF-03446962) is a highly humanized IgG2 monoclonal antibody against ALK-1. Ascrinvacumab has a Kd value of 7 nM for human ALK1. Ascrinvacumab has an inhibitory effect on TGF-β and can be used to study hepa...
T8399 Crizotinib hydrochloride PF-02341066 hydrochloride c-Met/HGFR , ROS , ALK , Autophagy , ROS Kinase
Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)
T22324 Ensartinib hydrochloride Ensartinib dihydrochloride,X-396 dihydrochloride Others , Trk receptor , c-Met/HGFR , ALK
Ensartinib hydrochloride (X-396 dihydrochloride) is a potent new-generation ALK inhibitor with high activity against CNS metastases and a broad range of known crizotinib-resistant ALK mutations. It potently inhibits both...
T16153 MS4078 ALK , Ligand for E3 Ligase
MS4078 is an inhibitor and aplastic lymphoma kinase (ALK) PROTAC (degrader) based on Cereblon ligand, with a Kd of 19 nM for binding affinity to ALK.
T61443 Trk-IN-7
Trk-IN-7 (compound I-6) is a highly potent inhibitor of TRK, exhibiting IC50 values ranging from 0.25-10 nM for TRKA, TRKB, and TRKC, respectively. In addition, Trk-IN-7 demonstrates notable inhibition against EML4-ALK (...
T73417 Con B-1
ConB-1 is a potent and selective ALK inhibitor with low toxicity to normal cells .
T83146 ALK-IN-27
ALK-IN-27 (compound 1) is a potent ALK inhibitor exhibiting antitumor activity, with an IC50 of 2.7 nM in Ba/F3 CLIP1-LTK cells [1].
T83856 AP-1
AP-1, a miniaturized proteolysis-targeting chimera (PROTAC) incorporating an anaplastic lymphoma kinase (ALK) ligand connected to (±)-thalidomide via an ultrashort linker, effectively degrades ALK fusion proteins such as...
T79394 ALK/EGFR-IN-3
ALK/EGFR-IN-3 is a dual ALK and EGFR inhibitor that demonstrates potent anti-proliferative effects on various cancer cell lines, including H1975, PC9, and Baf3-EML4-ALK, with respective IC50 values of 0.1360, 0.0332, and...
T38584 ALK-IN-12
ALK-IN-12 is a highly potent and orally active inhibitor of anaplastic lymphoma kinase (ALK), demonstrating an exceptional IC50 value of 0.18 nM. Additionally, ALK-IN-12 displays inhibitory activity against insulin-like ...
T74522 ALK-IN-21
ALK-IN-21 (Compound B10), a proficient ALK inhibitor targeting the ALKG1202R mutation, demonstrates significant inhibitory activity, with IC50 values of 4.59 nM against ALK WT, 2.07 nM against ALK L1196M, and 5.95 nM aga...
T77942 SIAIS164018 hydrochloride PROTACs
SIAIS164018 hydrochloride is a PROTAC-based degrader targeting ALK and EGFR, exhibiting IC50 values of 2.5 nM for ALK and 6.6 nM for ALK G1202R. It effectively suppresses cancer cell migration and invasion, induces G1 ce...
T9414 TPX-0131
TPX-0131 is a potent, selective, CNS-penetrant and orally active inhibitor of wild-type ALK ( IC 50 of 1.4 nM) and is potent against ALK-resistant mutation, e.g. G1202R ( IC 50 of 0.3 nM), L1196M ( IC 50 of 0.3 nM). TPX-...
T70060 PF-06463922 acetate
PF-06463922 acetate is a potent, selective brain-penetrable inhibitor of both anaplastic lymphoma kinase (ALK) and c-ros Oncogene 1 (ROS1) with strong activity against all known ALK and ROS1 mutants identified in patient...
T79393 ALK/EGFR-IN-2
ALK/EGFR-IN-2 is a potent dual inhibitor targeting ALK and EGFR, promoting apoptosis and G0/G1 cell cycle arrest in cancer cells. It effectively suppresses proliferation in H1975, PC9, and Baf3-EML4-ALK cancer cell lines...
T74570 SIAIS164018
SIAIS164018, a PROTAC-based ALK and EGFR degrader derived from Brigatinib, exhibits IC50 values of 2.5 nM for ALK and 6.6 nM for ALK G1202R. It significantly hampers cancer cell migration and invasion, induces G1 cell cy...
T62613 ALK5-IN-26
ALK5-IN-26 (EX-22) is an ALK (Activin receptor-like kinase) inhibitor. ALK5-IN-26 inhibits ALK5 (IC50 ≤ 1 nM).
T79363 APG-2449 ROS Kinase
APG-2449 is an orally active inhibitor targeting ALK, ROS1, and FAK, demonstrating antitumor efficacy in mouse models of non-small cell lung cancer (NSCLC) [1].
T37585 Ensartinib
Ensartinib (X-396) is a potent and dual ALK/MET inhibitor with IC50s of <0.4 nM and 0.74 nM, respectively. The ability of Ensartinib (X-396) to inhibit the growth of different cancer cell lines harboring ALK fusions or ...
T74489 SIAIS117
SIAIS117, a potent Brigatinib-PROTAC degrader, effectively degrades the ALK G1202R point mutation through its design based on Brigatinib and VHL-1 conjunction. It inhibits the proliferation of SR and H2228 cancer cell li...
T82869 Biotin-PEG-Alk (MW 600)
Biotin-PEG-Alk (MW 600) is a biotin-labeled, alkyne-functionalized polyethylene glycol utilized as a click chemistry reagent for protein, peptide, and oligonucleotide modification [1]. Containing an alkyne group, it is d...
T61872 Trk-IN-10
Trk-IN-10 (Compound 14j) is a highly effective inhibitor of TRK, with an IC50 of 0.86 nM against TrkA and 6.92 nM against TrkA G595R. As an RTK, Trk plays a crucial role as a drug target in solid tumors. Trk-IN-10 (IC50 ...

Compounds

ALK inhibitor 1
T10285
Synonym:
Target: FAK, IGF-1R, ALK
EML4-ALK kinase inhibitor 1
T11184
Synonym: EML4 ALK kinase inhibitor 1,EML4-​ALK kinase inhibitor 1
Target: ALK
ALK kinase inhibitor-1
T6409
Synonym: SAR348830
Target: Others
ALK-IN-1
T3059
Synonym: AP26113,Brigatinib,AP26113-analog
Target: EGFR, IGF-1R, ALK
ALK/ROS1-IN-1
T10286
Synonym:
Target: Others
F-1
T11254
Synonym:
Target: ROS, ALK, ROS Kinase
HG-14-10-04
T4015
Synonym:
Target: ALK
KRCA-0008
T2641
Synonym: KRCA 0008,KRCA0008
Target: ACK, ALK
R-268712
T16708
Synonym:
Target: ALK, TGF-beta/Smad
ALK/EGFR-IN-1
T79392
Synonym:
Target: EGFR
NVP-TAE 684
T2251
Synonym: TAE684
Target: Apoptosis, ALK
TRK/ALK-IN-1
T72931
Synonym:
Target:
ALK/ROS1 inhibitor 2e HCL
T67699L
Synonym: (R)-1-(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide hydrochloride(2365497-12-5 Free base)
Target: Apoptosis
Alectinib
T1936
Synonym: RG-7853,AF802,CH5424802,AF-802
Target: VEGFR, Tyrosine Kinases, ALK
Entrectinib
T3678
Synonym: RXDX-101,NMS-E628
Target: Trk receptor, ROS, ALK, Autophagy, ROS Kinase
Alectinib hydrochloride
T8387
Synonym: CH5424802 (Hydrochloride),AF-802 (Hydrochloride),RO5424802 (Hydrochloride)
Target: ALK
Lorlatinib
T3061
Synonym: PF-6463922,PF-06463922,Loratinib
Target: Apoptosis, Tyrosine Kinases, ROS, ALK, ROS Kinase
Ascrinvacumab
T76858
Synonym: PF-03446962
Target: ALK, TGF-beta/Smad
Crizotinib hydrochloride
T8399
Synonym: PF-02341066 hydrochloride
Target: c-Met/HGFR, ROS, ALK, Autophagy, ROS Kinase
Ensartinib hydrochloride
T22324
Synonym: Ensartinib dihydrochloride,X-396 dihydrochloride
Target: Others, Trk receptor, c-Met/HGFR, ALK
MS4078
T16153
Synonym:
Target: ALK, Ligand for E3 Ligase
Trk-IN-7
T61443
Synonym:
Target:
Con B-1
T73417
Synonym:
Target:
ALK-IN-27
T83146
Synonym:
Target:
AP-1
T83856
Synonym:
Target:
ALK/EGFR-IN-3
T79394
Synonym:
Target:
ALK-IN-12
T38584
Synonym:
Target:
ALK-IN-21
T74522
Synonym:
Target:
SIAIS164018 hydrochloride
T77942
Synonym:
Target: PROTACs
TPX-0131
T9414
Synonym:
Target:
PF-06463922 acetate
T70060
Synonym:
Target:
ALK/EGFR-IN-2
T79393
Synonym:
Target:
SIAIS164018
T74570
Synonym:
Target:
ALK5-IN-26
T62613
Synonym:
Target:
APG-2449
T79363
Synonym:
Target: ROS Kinase
Ensartinib
T37585
Synonym:
Target:
SIAIS117
T74489
Synonym:
Target:
Biotin-PEG-Alk (MW 600)
T82869
Synonym:
Target:
Trk-IN-10
T61872
Synonym:
Target:

Recombinant Proteins

Species：
Human (1433)
Mouse (234)
Cynomolgus (28)
Rat (27)
Chinese hamster (4)
RSV (4)
Canine (3)
Phleum pratense (3)
Human (2)
Human,Cynomolgus,Rhesus (2)
Expression System：
HEK293 (1333)
E. coli (204)
Baculovirus-Insect Cells (186)
CHO (14)
Human Cells (13)
Yeast (10)
Tag：
His (704)
hFc (234)
C-His-Avi (181)
Tag Free (106)
C-His (95)
His,GST (73)
C-hFc (56)
mFc (40)
His,AVI (39)
GST (38)
Cat No. Product Name Species Expression System
TMPY-01168 ALK-1 Protein, Human, Recombinant (His) Human HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPY-00650 ALK-1 Protein, Human, Recombinant (hFc) Human HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPJ-00304 ALK-1 Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-β superfamily of ligands, which mediates signaling of BMP9 (bone morphogenetic protein) and BMP10. ALK1 signaling is necessary for angi...
TMPK-00305 TGFBR1 Protein, Human, Recombinant (mFc & Avi) Human HEK293
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup...
TMPY-01059 BMPR2 Protein, Human, Recombinant (His) Human HEK293
The bone morphogenetic protein type II receptor (BMPR-II, or BMPR2), a receptor for the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) superfamily. Reduced expression or function of BMPR2 signalin...
TMPY-04774 ALK-2/ACVR1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-03678 ALK-1 Protein, Canine, Recombinant (hFc) Canine HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPY-03315 ALK-1 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPY-00310 ALK-1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPY-00662 ALK-1 Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPY-01096 ALK-2/ACVR1 Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-00757 ALK-1 Protein, Rat, Recombinant (His & hFc) Rat HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPJ-01158 ALK-2/ACVR1 Protein, Human, Recombinant (hFc) Human Human Cells
Activin RIA, also known as ALK-2, TSK-7L, SKR1, TSR-I, and ACTR-I, is a glycosylated 65 kDa type I receptor in the TGF-beta serine/threonine kinase receptor family. Binding of TGF-beta superfamily ligands induces formati...
TMPK-00767 SLPI Protein, Human, Recombinant (hFc) Human HEK293
Elafin and SLPI (secretory leucocyte protease inhibitor) have multiple important roles both in normal homoeostasis and at sites of inflammation. These include antiprotease and antimicrobial activity as well as modulation...
TMPK-00924 SLPI Protein, Mouse, Recombinant (hFc) Mouse HEK293
Elafin and SLPI (secretory leucocyte protease inhibitor) have multiple important roles both in normal homoeostasis and at sites of inflammation. These include antiprotease and antimicrobial activity as well as modulation...
TMPY-04366 ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST) Human Baculovirus-Insect Cells
Transforming growth factor, beta receptor I, also known as Transforming growth factor-beta receptor type I , Serine / threonine-protein kinase receptor R4, Activin receptor-like kinase 5, SKR4, ALK-5, and TGFBR1, is a si...
TMPY-05771 ALK-5 Protein, Human, Recombinant (hFc) Human HEK293
Transforming growth factor, beta receptor I, also known as Transforming growth factor-beta receptor type I , Serine / threonine-protein kinase receptor R4, Activin receptor-like kinase 5, SKR4, ALK-5, and TGFBR1, is a si...
TMPJ-01178 TGFBR1 Protein, Mouse, Recombinant (hFc) Mouse Human Cells
TGF-beta RI, also called ALK-5, is an approximately 55 kDa type I transmembrane serine/threonine receptor kinase. In the presence of TGF-beta, TGF-beta RI forms a complex with, and is phosphorylated by, TGF-beta RII. Pho...
TMPY-01358 ALK-5 Protein, Human, Recombinant (His & hFc) Human HEK293
Transforming growth factor, beta receptor I, also known as Transforming growth factor-beta receptor type I , Serine / threonine-protein kinase receptor R4, Activin receptor-like kinase 5, SKR4, ALK-5, and TGFBR1, is a si...
TMPY-00683 BMPR2 Protein, Human, Recombinant (His & hFc) Human HEK293
The bone morphogenetic protein type II receptor (BMPR-II, or BMPR2), a receptor for the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) superfamily. Reduced expression or function of BMPR2 signalin...
TMPK-00306 TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated Human HEK293
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup...
TMPY-00658 ALK-2/ACVR1 Protein, Human, Recombinant (His & hFc) Human HEK293
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-01384 Endoglin/CD105 Protein, Human, Recombinant (His) Human HEK293
Endoglin, also known as CD105, is a type I homodimeric transmembrane glycoprotein with a large, disulfide-linked, extracellular region and a short, constitutively phosphorylated cytoplasmic tail. Endoglin contains an RGD...
TMPY-03707 ALK-2/ACVR1 Protein, Canine, Recombinant (His) Canine HEK293
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-03247 ALK-2/ACVR1 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-00486 ALK-7 Protein, Human, Recombinant (hFc) Human HEK293
ALK-7, also known as ALK7 and ACVR1C, belongs to the ALK family. It is a type I receptor for the TGFB family of signaling molecules. TGF-β is the prototype of a protein superfamily which, in humans, contains at least 35 ...
TMPY-03706 ALK-2/ACVR1 Protein, Canine, Recombinant (hFc) Canine HEK293
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-03157 ALK-2/ACVR1 Protein, Rat, Recombinant (hFc) Rat HEK293
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-03187 ALK-7 Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
ALK-7, also known as ALK7 and ACVR1C, belongs to the ALK family. It is a type I receptor for the TGFB family of signaling molecules. TGF-β is the prototype of a protein superfamily which, in humans, contains at least 35 ...
TMPJ-00256 Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated Human Human Cells
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are...
TMPJ-00255 TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated Human Human Cells
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are...
TMPY-01615 Endoglin/CD105 Protein, Mouse, Recombinant (His) Mouse HEK293
Endoglin, also known as CD105, is a type I homodimeric transmembrane glycoprotein with a large, disulfide-linked, extracellular region and a short, constitutively phosphorylated cytoplasmic tail. Endoglin contains an RGD...
TMPY-00783 Endoglin/CD105 Protein, Human, Recombinant (hFc) Human HEK293
Endoglin, also known as CD105, is a type I homodimeric transmembrane glycoprotein with a large, disulfide-linked, extracellular region and a short, constitutively phosphorylated cytoplasmic tail. Endoglin contains an RGD...
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus-Insect Cells
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Human HEK293
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th...
TMPY-02501 CD3D & CD3E Heterodimer Protein, Human, Recombinant Human HEK293
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 cells.
TMPY-03745 CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) Human HEK293
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 with Flag and His tag. The predicted molecular weight is 31.05 kDa. Accession number: P04234-1&P07766-1
TMPY-02794 TLR2 Protein, Human, Recombinant (aa 1-587, His) Human Baculovirus-Insect Cells
TLR2, also known as CD282, is a member of the Toll-like receptor (TLR) family. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They play a fundamental role in pathoge...
TMPY-03947 CD48 Protein, Human, Recombinant (hFc) Human HEK293
Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD4...
TMPY-03481 IL-1R2 Protein, Human, Recombinant Human HEK293
Interleukin 1 receptor, type II (IL1R2) also known as CD121b (Cluster of Differentiation 121b) is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein binds interleukin alpha (IL1A), interl...
TMPK-00114 C-Reactive Protein /CRP Protein, Human, Recombinant (His) Human HEK293
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate ...
TMPY-00740 SDF-1 Protein, Human, Recombinant (hFc) Human HEK293
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-04384 Src Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C...
TMPK-01151 MXRA8 Protein, Human, Recombinant (His) Human HEK293
Mxra8 is a recently described receptor for multiple alphaviruses, including Chikungunya (CHIKV), Mayaro (MAYV), Ross River (RRV), and O'nyong nyong (ONNV) viruses.
TMPK-01074 CD163 Protein, Human, Recombinant (His & Avi) Human HEK293
The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in ...
TMPK-00383 ACE2/ACEH Protein, Human, Recombinant (His & Avi) Human HEK293
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angio...
TMPY-02525 RGMA Protein, Human, Recombinant (His) Human HEK293
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein th...
TMPY-04753 IRE1 Protein, Human, Recombinant (aa 465-977) Human Baculovirus-Insect Cells
Endoplasmic reticulum stress and hypoxia are necessary components of malignant tumors growth and suppression of ERN1 (from endoplasmic reticulum to nuclei-1) signalling pathway, which is linked to the apoptosis and cell ...
TMPY-04413 IRE1 Protein, Human, Recombinant (aa 465-977, His & GST) Human Baculovirus-Insect Cells
Endoplasmic reticulum stress and hypoxia are necessary components of malignant tumors growth and suppression of ERN1 (from endoplasmic reticulum to nuclei-1) signalling pathway, which is linked to the apoptosis and cell ...
TMPK-01393 Tenascin Protein, Mouse, Recombinant (His) Mouse HEK293
Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein modifications. It is highly conserved amongst vertebrates,...
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ALK-1 Protein, Human, Recombinant (His)
TMPY-01168
Species: Human
Expression System: HEK293
ALK-1 Protein, Human, Recombinant (hFc)
TMPY-00650
Species: Human
Expression System: HEK293
ALK-1 Protein, Mouse, Recombinant (hFc)
TMPJ-00304
Species: Mouse
Expression System: Human Cells
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
TMPK-00305
Species: Human
Expression System: HEK293
BMPR2 Protein, Human, Recombinant (His)
TMPY-01059
Species: Human
Expression System: HEK293
ALK-2/ACVR1 Protein, Human, Recombinant (His)
TMPY-04774
Species: Human
Expression System: Baculovirus-Insect Cells
ALK-1 Protein, Canine, Recombinant (hFc)
TMPY-03678
Species: Canine
Expression System: HEK293
ALK-1 Protein, Cynomolgus, Recombinant (hFc)
TMPY-03315
Species: Cynomolgus
Expression System: HEK293
ALK-1 Protein, Cynomolgus, Recombinant (His)
TMPY-00310
Species: Cynomolgus
Expression System: HEK293
ALK-1 Protein, Mouse, Recombinant (His & hFc)
TMPY-00662
Species: Mouse
Expression System: HEK293
ALK-2/ACVR1 Protein, Mouse, Recombinant (His & hFc)
TMPY-01096
Species: Mouse
Expression System: HEK293
ALK-1 Protein, Rat, Recombinant (His & hFc)
TMPY-00757
Species: Rat
Expression System: HEK293
ALK-2/ACVR1 Protein, Human, Recombinant (hFc)
TMPJ-01158
Species: Human
Expression System: Human Cells
SLPI Protein, Human, Recombinant (hFc)
TMPK-00767
Species: Human
Expression System: HEK293
SLPI Protein, Mouse, Recombinant (hFc)
TMPK-00924
Species: Mouse
Expression System: HEK293
ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST)
TMPY-04366
Species: Human
Expression System: Baculovirus-Insect Cells
ALK-5 Protein, Human, Recombinant (hFc)
TMPY-05771
Species: Human
Expression System: HEK293
TGFBR1 Protein, Mouse, Recombinant (hFc)
TMPJ-01178
Species: Mouse
Expression System: Human Cells
ALK-5 Protein, Human, Recombinant (His & hFc)
TMPY-01358
Species: Human
Expression System: HEK293
BMPR2 Protein, Human, Recombinant (His & hFc)
TMPY-00683
Species: Human
Expression System: HEK293
TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated
TMPK-00306
Species: Human
Expression System: HEK293
ALK-2/ACVR1 Protein, Human, Recombinant (His & hFc)
TMPY-00658
Species: Human
Expression System: HEK293
Endoglin/CD105 Protein, Human, Recombinant (His)
TMPY-01384
Species: Human
Expression System: HEK293
ALK-2/ACVR1 Protein, Canine, Recombinant (His)
TMPY-03707
Species: Canine
Expression System: HEK293
ALK-2/ACVR1 Protein, Cynomolgus, Recombinant (hFc)
TMPY-03247
Species: Cynomolgus
Expression System: HEK293
ALK-7 Protein, Human, Recombinant (hFc)
TMPY-00486
Species: Human
Expression System: HEK293
ALK-2/ACVR1 Protein, Canine, Recombinant (hFc)
TMPY-03706
Species: Canine
Expression System: HEK293
ALK-2/ACVR1 Protein, Rat, Recombinant (hFc)
TMPY-03157
Species: Rat
Expression System: HEK293
ALK-7 Protein, Rhesus, Recombinant (hFc)
TMPY-03187
Species: Rhesus
Expression System: HEK293
Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00256
Species: Human
Expression System: Human Cells
TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated
TMPJ-00255
Species: Human
Expression System: Human Cells
Endoglin/CD105 Protein, Mouse, Recombinant (His)
TMPY-01615
Species: Mouse
Expression System: HEK293
Endoglin/CD105 Protein, Human, Recombinant (hFc)
TMPY-00783
Species: Human
Expression System: HEK293
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
TMPY-04451
Species: Human
Expression System: Baculovirus-Insect Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
TMPY-03878
Species: Human
Expression System: HEK293
CD3D & CD3E Heterodimer Protein, Human, Recombinant
TMPY-02501
Species: Human
Expression System: HEK293
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
TMPY-03745
Species: Human
Expression System: HEK293
TLR2 Protein, Human, Recombinant (aa 1-587, His)
TMPY-02794
Species: Human
Expression System: Baculovirus-Insect Cells
CD48 Protein, Human, Recombinant (hFc)
TMPY-03947
Species: Human
Expression System: HEK293
IL-1R2 Protein, Human, Recombinant
TMPY-03481
Species: Human
Expression System: HEK293
C-Reactive Protein /CRP Protein, Human, Recombinant (His)
TMPK-00114
Species: Human
Expression System: HEK293
SDF-1 Protein, Human, Recombinant (hFc)
TMPY-00740
Species: Human
Expression System: HEK293
Src Protein, Human, Recombinant (His & GST)
TMPY-04384
Species: Human
Expression System: Baculovirus-Insect Cells
MXRA8 Protein, Human, Recombinant (His)
TMPK-01151
Species: Human
Expression System: HEK293
CD163 Protein, Human, Recombinant (His & Avi)
TMPK-01074
Species: Human
Expression System: HEK293
ACE2/ACEH Protein, Human, Recombinant (His & Avi)
TMPK-00383
Species: Human
Expression System: HEK293
RGMA Protein, Human, Recombinant (His)
TMPY-02525
Species: Human
Expression System: HEK293
IRE1 Protein, Human, Recombinant (aa 465-977)
TMPY-04753
Species: Human
Expression System: Baculovirus-Insect Cells
IRE1 Protein, Human, Recombinant (aa 465-977, His & GST)
TMPY-04413
Species: Human
Expression System: Baculovirus-Insect Cells
Tenascin Protein, Mouse, Recombinant (His)
TMPK-01393
Species: Mouse
Expression System: HEK293
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